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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK14
All Species:
35.76
Human Site:
Y220
Identified Species:
60.51
UniProt:
O94921
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94921
NP_036527.1
469
53057
Y220
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Chimpanzee
Pan troglodytes
XP_519189
469
53035
Y220
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001102520
469
53072
Y220
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Dog
Lupus familis
XP_532455
469
53036
Y220
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O35495
469
52977
Y220
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Rat
Rattus norvegicus
O35831
523
59414
Y277
L
D
K
D
L
K
Q
Y
M
D
D
C
G
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516045
337
37621
S124
P
K
F
G
K
A
D
S
Y
E
K
L
E
K
L
Chicken
Gallus gallus
XP_418647
773
84016
Y524
V
H
T
D
L
C
Q
Y
M
D
K
H
P
G
G
Frog
Xenopus laevis
Q6DJM7
435
49211
P196
K
H
P
G
G
L
N
P
E
N
V
K
L
F
L
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
R200
L
S
Y
I
H
G
R
R
I
L
H
R
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523904
522
59750
Y290
V
N
T
D
L
S
Q
Y
M
E
K
H
P
G
G
Honey Bee
Apis mellifera
XP_624994
494
56118
Y250
V
H
T
D
L
S
Q
Y
M
E
R
Y
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
E81
K
R
L
Y
L
V
F
E
Y
L
D
L
D
L
K
Baker's Yeast
Sacchar. cerevisiae
P17157
305
34888
Y92
M
D
N
D
L
K
K
Y
M
D
S
R
T
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.7
99.1
N.A.
98.5
43
N.A.
60.7
58.5
85.2
51.5
N.A.
48.4
50
N.A.
N.A.
Protein Similarity:
100
99.5
99.7
100
N.A.
99.3
59
N.A.
63.3
59.5
89.3
63.1
N.A.
61.2
63.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
40
N.A.
6.6
100
6.6
0
N.A.
80
60
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
13.3
100
13.3
20
N.A.
93.3
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
43.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
43
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
15
0
72
0
0
8
0
0
58
15
0
15
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
22
0
0
8
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
15
8
8
0
0
0
0
0
0
15
50
65
% G
% His:
0
58
0
0
8
0
0
0
0
0
8
50
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
15
8
8
0
8
15
8
0
0
0
58
8
0
8
15
% K
% Leu:
15
0
8
0
79
8
0
0
0
15
0
15
8
15
15
% L
% Met:
8
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
8
0
0
0
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
65
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
8
0
0
8
15
0
0
0
% R
% Ser:
0
8
0
0
0
15
0
8
0
0
8
0
0
15
0
% S
% Thr:
0
0
58
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
58
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
72
15
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _